Allyl isothiocyanate as a potential inducer of paraoxonase-1 - studies in cultured hepatocytes and in mice
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چکیده
منابع مشابه
Genistein as a potential inducer of the anti-atherogenic enzyme paraoxonase-1: studies in cultured hepatocytes in vitro and in rat liver in vivo
A number of cardioprotective effects, including the reduced oxidation of the low-density lipoprotein (LDL) particles, have been attributed to dietary soy isoflavones. Paraoxonase 1 (PON1), an enzyme mainly synthesized in the liver, may exhibit anti-atherogenic activity by protecting LDL from oxidation. Thus, dietary and pharmacological inducers of PON1 may decrease cardiovascular disease risk. ...
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Allyl isothiocyanate as a cancer chemopreventive phytochemical.
Allyl isothiocyanate (AITC), which occurs in many common cruciferous vegetables, is widely and often frequently consumed by humans. Besides antimicrobial activity against a wide spectrum of pathogens, it showed anticancer activity in both cultured cancer cells and animal models, although the underlining mechanisms remain largely undefined. Bioavailability of AITC is extremely high, as nearly 90...
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ژورنال
عنوان ژورنال: IUBMB Life
سال: 2011
ISSN: 1521-6543
DOI: 10.1002/iub.587